Biomarker Report from the Phase II Lamotrigine Trial in Secondary Progressive MS – Neurofilament as a Surrogate of Disease Progression

OBJECTIVE: Lamotrigine trial in SPMS was a randomised control trial to assess whether partial blockade of sodium channels has a neuroprotective effect. The current study was an additional study to investigate the value of neurofilament (NfH) and other biomarkers in predicting prognosis and/or respon...

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Autors principals: Gnanapavan, Sharmilee, Grant, Donna, Morant, Steve, Furby, Julian, Hayton, Tom, Teunissen, Charlotte E., Leoni, Valerio, Marta, Monica, Brenner, Robert, Palace, Jacqueline, Miller, David H., Kapoor, Raj, Giovannoni, Gavin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731296/
https://ncbi.nlm.nih.gov/pubmed/23936370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070019
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