Rebmab200, a Humanized Monoclonal Antibody Targeting the Sodium Phosphate Transporter NaPi2b Displays Strong Immune Mediated Cytotoxicity against Cancer: A Novel Reagent for Targeted Antibody Therapy of Cancer

NaPi2b, a sodium-dependent phosphate transporter, is highly expressed in ovarian carcinomas and is recognized by the murine monoclonal antibody MX35. The antibody had shown excellent targeting to ovarian cancer in several early phase clinical trials but being murine the antibody's full therapeu...

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Xehetasun bibliografikoak
Egile Nagusiak: dos Santos, Mariana Lopes, Yeda, Fernanda Perez, Tsuruta, Lilian Rumi, Horta, Bruno Brasil, Pimenta, Alécio A., Degaki, Theri Leica, Soares, Ibere C., Tuma, Maria Carolina, Okamoto, Oswaldo Keith, Alves, Venancio A. F., Old, Lloyd J., Ritter, Gerd, Moro, Ana Maria
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729455/
https://ncbi.nlm.nih.gov/pubmed/23936189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070332
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