Population genomics of post-vaccine changes in pneumococcal epidemiology

Whole genome sequencing of 616 asymptomatically carried pneumococci was used to study the impact of the 7-valent pneumococcal conjugate vaccine. Comparison of closely related isolates revealed the role of transformation in facilitating capsule switching to non-vaccine serotypes and the emergence of...

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Bibliografische gegevens
Hoofdauteurs: Croucher, Nicholas J., Finkelstein, Jonathan A., Pelton, Stephen I., Mitchell, Patrick K., Lee, Grace M., Parkhill, Julian, Bentley, Stephen D., Hanage, William P., Lipsitch, Marc
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725542/
https://ncbi.nlm.nih.gov/pubmed/23644493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2625
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