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AMPK: a contextual oncogene or tumor suppressor?
The AMP-activated protein kinase (AMPK) functions to monitor and maintain energy homeostasis at the cellular and organismal level. AMPK was perceived historically primarily as a component of the LKB1/STK11 tumor suppressor (LKB1 mutations cause the Peutz Jegher’s cancer predisposition syndrome, PJS)...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3725287/ https://ncbi.nlm.nih.gov/pubmed/23644529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3876 |
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