Persistent Low Level of Osterix Accelerates Interleukin-6 Production and Impairs Regeneration after Tissue Injury

Osterix (Osx) is an essential transcription factor for osteoblast differentiation and bone formation. Osx knockout show a complete absence of bone formation, whereas Osx conditional knockout in osteoblasts produce an osteopenic phenotype after birth. Here, we questioned whether Osx has a potential r...

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Auteurs principaux: Baek, Wook-Young, Park, Seung-Yoon, Kim, Yeo Hyang, Lee, Min-A, Kwon, Tae-Hwan, Park, Kwon-Moo, de Crombrugghe, Benoit, Kim, Jung-Eun
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724732/
https://ncbi.nlm.nih.gov/pubmed/23922826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069859
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