p16 Stimulates CDC42-Dependent Migration of Hepatocellular Carcinoma Cells

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide. Tumor dissemination to the extra-hepatic region of the portal vein, lymph nodes, lungs or bones contributes to the high mortality seen in HCC; yet, the molecular mechanisms responsible for HCC metastasis remain unc...

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Bibliographic Details
Main Authors: Chen, Ya-Wen, Chu, Hsiao-Chien, Ze-Shiang Lin, Shiah, Wei-Jyh, Chou, Chen-Pin, Klimstra, David S., Lewis, Brian C.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722281/
https://ncbi.nlm.nih.gov/pubmed/23894465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069389
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