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Metabolic Studies in Familial Hypercholesterolemia: EVIDENCE FOR A GENE-DOSAGE EFFECT IN VIVO

To investigate the gene-dosage effect in familial hypercholesterolemia (FH), metabolic studies were conducted in a group of well-characterized patients with either heterozygous (n = 7) or homozygous (n = 7) FH and the results were compared to those obtained in normal subjects (n = 6). The turnover o...

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Detalhes bibliográficos
Main Authors: Bilheimer, David W., Stone, Neil J., Grundy, Scott M.
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC372147/
https://ncbi.nlm.nih.gov/pubmed/222811
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