Coenzyme Q10 Ameliorates Pain and Cartilage Degradation in a Rat Model of Osteoarthritis by Regulating Nitric Oxide and Inflammatory Cytokines

OBJECTIVE: To investigate the effect of CoenzymeQ10 (CoQ10) on pain severity and cartilage degeneration in an experimental model of rat osteoarthritis (OA). MATERIALS AND METHODS: OA was induced in rats by intra-articular injection of monosodium iodoacetate (MIA) to the knee. Oral administration of...

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Autori principali: Lee, Jennifer, Hong, Yeon Sik, Jeong, Jeong Hee, Yang, Eun Ji, Jhun, Joo Yeon, Park, Mi Kyoung, Jung, Young Ok, Min, Jun Ki, Kim, Ho Youn, Park, Sung Hwan, Cho, Mi-La
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718733/
https://ncbi.nlm.nih.gov/pubmed/23894457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069362
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