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Interaction between Trehalose and MTHase from Sulfolobus solfataricus Studied by Theoretical Computation and Site-Directed Mutagenesis

Maltooligosyltrehalose trehalohydrolase (MTHase) catalyzes the release of trehalose by cleaving the α-1,4-glucosidic linkage next to the α-1,1-linked terminal disaccharide of maltooligosyltrehalose. Computer simulation using the hydrogen bond analysis, free energy decomposition, and computational al...

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Detalhes bibliográficos
Main Authors: Fu, Chien-wei, Wang, Yu-Ping, Fang, Tsuei-Yun, Lin, Thy-Hou
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716775/
https://ncbi.nlm.nih.gov/pubmed/23894317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068565
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