Importance of helper T-cell activation in dendritic cell-based anticancer immunotherapy

Dendritic cell-based anticancer immunotherapy is feasible, safe and results in the induction of tumor-specific immune responses, at least in a fraction of vaccinated patients. The concomitant activation of cytotoxic and helper T cells, by loading DCs with peptides or electroporating them with the co...

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Main Authors: Schreibelt, Gerty, Bol, Kalijn F., Aarntzen, Erik HJG, Gerritsen, Winald R, Punt, Cornelis JA, Figdor, Carl G, de Vries, I Jolanda M
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2013
Teme:
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716737/
https://ncbi.nlm.nih.gov/pubmed/23894702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.24440
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