Prospective Phase II Single-Center Study of the Safety of a Single Very High Dose of Liposomal Amphotericin B for Antifungal Prophylaxis in Patients with Acute Myeloid Leukemia

Some preclinical and pharmacokinetic studies suggested the variable safety and the potential efficacy of an antifungal prophylaxis with a single high dose of liposomal amphotericin B (L-AmB) in high-risk patients. An open-label, prospective study was conducted with 48 adults receiving induction chem...

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Autori principali: Annino, Luciana, Chierichini, Anna, Anaclerico, Barbara, Finolezzi, Erica, Norata, Marianna, Cortese, Stefania, Cassetta, Maria Iris, Fallani, Stefania, Novelli, Andrea, Girmenia, Corrado
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
Soggetti:
Clinical Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716179/
https://ncbi.nlm.nih.gov/pubmed/23529741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00155-13
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