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Pathogenesis of type 1 diabetes: lessons from natural history studies of high-risk individuals
Type 1 diabetes (T1D) is an autoimmune disease characterized by known genetic risk factors with T cell–mediated infiltration and destruction of the beta cells within pancreatic islets. Autoantibodies are the most significant preclinical marker of T1D, and birth cohort studies have provided important...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Publishing Ltd
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3715099/ https://ncbi.nlm.nih.gov/pubmed/23360422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.12021 |
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