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Caspase-12 controls West Nile virus infection via the viral RNA receptor RIG-I
Caspase-12 has been shown to negatively modulate inflammasome signaling during bacterial infection. Its function in viral immunity, however, has not been characterized. We now report an important role for caspase-12 in controlling viral infection via the pattern-recognition receptor RIG-I. After cha...
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| Main Authors: | , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3712356/ https://ncbi.nlm.nih.gov/pubmed/20818395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1933 |
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