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Amelioration of Hypoglycemia Via Somatostatin Receptor Type 2 Antagonism in Recurrently Hypoglycemic Diabetic Rats

Selective antagonism of somatostatin receptor type 2 (SSTR2) normalizes glucagon and corticosterone responses to hypoglycemic clamp in diabetic rats. The purpose of this study was to determine whether SSTR2 antagonism (SSTR2a) ameliorates hypoglycemia in response to overinsulinization in diabetic ra...

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Autori principali: Yue, Jessica T.Y., Riddell, Michael C., Burdett, Elena, Coy, David H., Efendic, Suad, Vranic, Mladen
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712070/
https://ncbi.nlm.nih.gov/pubmed/23434929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1523
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