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CtBP1 is expressed in melanoma and represses the transcription of p16INK4a and Brca1

Carboxyl-terminal binding protein 1 (CtBP1) has been shown to suppress the transcription of several tumor suppressors in vitro. Paradoxically, a previous report showed that CtBP1 mRNA was down-regulated in melanoma. Using immunostaining, we found that a large percentage of human melanomas were posit...

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Detalhes bibliográficos
Main Authors: Deng, Hui, Liu, Jing, Deng, Yu, Han, Gangwen, Shellman, Yiqun G., Robinson, Steven, Tentler, John, Robinson, William, Norris, David A., Wang, Xiao-Jing, Zhang, Qinghong
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711675/
https://ncbi.nlm.nih.gov/pubmed/23303449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2012.487
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