Testosterone Depletion in Adult Male Rats Increases Mossy Fiber Transmission, LTP, and Sprouting in Area CA3 of Hippocampus

Androgens have dramatic effects on neuronal structure and function in hippocampus. However, androgen depletion does not always lead to hippocampal impairment. To address this apparent paradox, we evaluated the hippocampus of adult male rats after gonadectomy (Gdx) or sham surgery. Surprisingly, Gdx...

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Main Authors: Skucas, Vanessa A., Duffy, Aine M., Harte-Hargrove, Lauren C., Magagna-Poveda, Alejandra, Radman, Thomas, Chakraborty, Goutam, Schroeder, Charles E., MacLusky, Neil J., Scharfman, Helen E.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711621/
https://ncbi.nlm.nih.gov/pubmed/23392664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3857-12.2013
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