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Interaction between Her2 and Beclin-1 Proteins Underlies a New Mechanism of Reciprocal Regulation

Beclin-1 is a key regulator of autophagy that functions in the context of two phase-specific complexes in the initiation and maturation of autophagosomes. Its known interacting proteins include autophagy effectors, Bcl-2 family members, and organelle membrane anchor proteins. Here we report a newly...

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Hlavní autoři: Han, Jie, Hou, Wen, Lu, Caisheng, Goldstein, Leslie A., Stolz, Donna B., Watkins, Simon C., Rabinowich, Hannah
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711298/
https://ncbi.nlm.nih.gov/pubmed/23703612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.461350
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