Translocation Products in Acute Myeloid Leukemia Activate the Wnt Signaling Pathway in Hematopoietic Cells

The acute myeloid leukemia (AML)-associated translocation products AML1-ETO, PML-retinoic acid receptor alpha (RARα), and PLZF-RARα encode aberrant transcription factors. Several lines of evidence suggest similar pathogenetic mechanisms for these fusion proteins. We used high-density oligonucleotide...

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Autores principales: Müller-Tidow, Carsten, Steffen, Björn, Cauvet, Thomas, Tickenbrock, Lara, Ji, Ping, Diederichs, Sven, Sargin, Bülent, Köhler, Gabriele, Stelljes, Matthias, Puccetti, Elena, Ruthardt, Martin, deVos, Sven, Hiebert, Scott W., Koeffler, H. Phillip, Berdel, Wolfgang E., Serve, Hubert
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Cell Growth and Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC371102/
https://ncbi.nlm.nih.gov/pubmed/15024077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.7.2890-2904.2004
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