Mutated and Bacteriophage T4 Nanoparticle Arrayed F1-V Immunogens from Yersinia pestis as Next Generation Plague Vaccines

Pneumonic plague is a highly virulent infectious disease with 100% mortality rate, and its causative organism Yersinia pestis poses a serious threat for deliberate use as a bioterror agent. Currently, there is no FDA approved vaccine against plague. The polymeric bacterial capsular protein F1, a key...

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Main Authors: Tao, Pan, Mahalingam, Marthandan, Kirtley, Michelle L., van Lier, Christina J., Sha, Jian, Yeager, Linsey A., Chopra, Ashok K., Rao, Venigalla B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2013
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708895/
https://ncbi.nlm.nih.gov/pubmed/23853602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003495
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