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1,25-dihydroxyvitamin D3 and its nuclear receptor repress human α(1)(I) collagen expression and type I collagen formation

BACKGROUND: Vitamin D deficiency is common in chronic liver disease particularly in those with severe liver fibrosis. Aims: To determine the effect of 1,25-dihydroxyvitamin D3 (1,25-(OH)(2)D(3)) on the human α(1)(I) collagen promoter and collagen formation by human stellate LX-2 cells and the mechan...

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Bibliographic Details
Main Authors: Potter, James J., Liu, Xiaopu, Koteish, Ayman, Mezey, Esteban
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707129/
https://ncbi.nlm.nih.gov/pubmed/23413886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.12122
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