CPEB1, a histone-modified hypomethylated gene, is regulated by miR-101 and involved in cell senescence in glioma

Epigenetic mechanisms have important roles in carcinogenesis. We certified that the mRNA translation-related gene cytoplasmic polyadenylation element-binding protein 1 (CPEB1) is hypomethylated and overexpressed in glioma cells and tissues. The knockdown of CPEB1 reduced cell senescence by regulatin...

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Autori principali: Xiaoping, L, Zhibin, Y, Wenjuan, L, Zeyou, W, Gang, X, Zhaohui, L, Ying, Z, Minghua, W, Guiyuan, L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702288/
https://ncbi.nlm.nih.gov/pubmed/23788032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.197
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