Oncolytic Adenovirus Expressing IL-23 and p35 Elicits IFN-γ- and TNF-α-Co-Producing T Cell-Mediated Antitumor Immunity

Cytokine immunogene therapy is a promising strategy for cancer treatment. Interleukin (IL)-12 boosts potent antitumor immunity by inducing T helper 1 cell differentiation and stimulating cytotoxic T lymphocyte and natural killer cell cytotoxicity. IL-23 has been proposed to have similar but not over...

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Bibliographic Details
Main Authors: Choi, Il-Kyu, Li, Yan, Oh, Eonju, Kim, Jaesung, Yun, Chae-Ok
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701076/
https://ncbi.nlm.nih.gov/pubmed/23844018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067512
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