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Tetraspanin CD9 Promotes the Invasive Phenotype of Human Fibrosarcoma Cells via Upregulation of Matrix Metalloproteinase-9

Tumor cell metastasis, a process which increases the morbidity and mortality of cancer patients, is highly dependent upon matrix metalloproteinase (MMP) production. Small molecule inhibitors of MMPs have proven unsuccessful at reducing tumor cell invasion in vivo. Therefore, finding an alternative a...

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Detalhes bibliográficos
Main Authors: Herr, Michael J., Kotha, Jayaprakash, Hagedorn, Nikolaus, Smith, Blake, Jennings, Lisa K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696041/
https://ncbi.nlm.nih.gov/pubmed/23840773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067766
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