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Tetraspanin CD9 Promotes the Invasive Phenotype of Human Fibrosarcoma Cells via Upregulation of Matrix Metalloproteinase-9

Tumor cell metastasis, a process which increases the morbidity and mortality of cancer patients, is highly dependent upon matrix metalloproteinase (MMP) production. Small molecule inhibitors of MMPs have proven unsuccessful at reducing tumor cell invasion in vivo. Therefore, finding an alternative a...

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Hlavní autoři: Herr, Michael J., Kotha, Jayaprakash, Hagedorn, Nikolaus, Smith, Blake, Jennings, Lisa K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696041/
https://ncbi.nlm.nih.gov/pubmed/23840773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067766
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