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Tetraspanin CD9 Promotes the Invasive Phenotype of Human Fibrosarcoma Cells via Upregulation of Matrix Metalloproteinase-9

Tumor cell metastasis, a process which increases the morbidity and mortality of cancer patients, is highly dependent upon matrix metalloproteinase (MMP) production. Small molecule inhibitors of MMPs have proven unsuccessful at reducing tumor cell invasion in vivo. Therefore, finding an alternative a...

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Main Authors: Herr, Michael J., Kotha, Jayaprakash, Hagedorn, Nikolaus, Smith, Blake, Jennings, Lisa K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696041/
https://ncbi.nlm.nih.gov/pubmed/23840773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067766
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