REGULATION OF LUNG CANCER METASTASIS BY Klf4-Numb-like SIGNALING

Metastatic traits appear to be acquired by transformed cells with progenitor-like cancer-initiating properties, but there remains little mechanistic insight into this linkage. In this report, we show that the polarity protein Numbl, which is expressed normally in neuronal progenitors, becomes overex...

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Bibliographic Details
Main Authors: Vaira, Valentina, Faversani, Alice, Martin, Nina M., Garlick, David S., Ferrero, Stefano, Nosotti, Mario, Kissil, Joseph L., Bosari, Silvano, Altieri, Dario C.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695627/
https://ncbi.nlm.nih.gov/pubmed/23440423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-4232
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