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Utilizing protein structure to identify non-random somatic mutations
BACKGROUND: Human cancer is caused by the accumulation of somatic mutations in tumor suppressors and oncogenes within the genome. In the case of oncogenes, recent theory suggests that there are only a few key “driver” mutations responsible for tumorigenesis. As there have been significant pharmacolo...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3691676/ https://ncbi.nlm.nih.gov/pubmed/23758891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-190 |
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