Toxicity of 2-deoxygalactose to Saccharomyces cerevisiae cells constitutively synthesizing galactose-metabolizing enzymes.

Analysis of 400 independent spontaneous mutations conferring 2-deoxygalactose resistance upon cells constitutive for the galactose pathway suggests that toxicity is due to 2-deoxygalactose-1-phosphate. Selection for and against growth on galactose in the same strain is now possible; application to s...

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Bibliographic Details
Main Author: Platt, T
Format: Artigo
Language:Inglês
Published: 1984
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC368858/
https://ncbi.nlm.nih.gov/pubmed/6328283
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