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Quality risk management of top spray fluidized bed process for antihypertensive drug formulation with control strategy engendered by Box-behnken experimental design space

INTRODUCTION: Lacidipine (LCDP) is a very low soluble and highly biovariable calcium channel blocker used in the treatment of hypertension. To increase its apparent solubility and to reduce its biovariability, solid dispersion fluid bed processing technology was explored, as it produces highly dispe...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Mukharya, Amit, Patel, Paresh U, Shenoy, Dinesh, Chaudhary, Shivang
פורמט: Artigo
שפה:Inglês
יצא לאור: Medknow Publications & Media Pvt Ltd 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687233/
https://ncbi.nlm.nih.gov/pubmed/23799202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2230-973X.108960
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