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Angiotensin-converting enzyme inhibition reduces food intake, weight gain and improves glucose tolerance in melanocortin-4 receptor deficient female rats

Functional loss of melanocortin-4 receptor (MC4R) activity leads to hyperphagia and an obese, glucose intolerant phenotype. We have previously established that inhibition of angiotensin-converting enzyme (ACE) reduces food intake, body weight and glucose homeostasis in diet-induced obesity. The curr...

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Bibliografiske detaljer
Main Authors: Mul, Joram D., Seeley, Randy J., Woods, Stephen C., Begg, Denovan P.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681872/
https://ncbi.nlm.nih.gov/pubmed/23416175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.physbeh.2013.01.013
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