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Host Defense and Recruitment of Foxp3(+) T Regulatory Cells to the Lungs in Chronic Mycobacterium tuberculosis Infection Requires Toll-like Receptor 2

Acute resistance to low dose M. tuberculosis (Mtb) infection is not dependent on Toll-like receptor (TLR) 2. However, whether TLR2 contributes to resistance in chronic Mtb infection has remained uncertain. Here we report that, following low dose aerosol infection with Mtb, mice lacking TLR2 (TLR2KO)...

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書目詳細資料
Main Authors: McBride, Amanda, Konowich, Jill, Salgame, Padmini
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681744/
https://ncbi.nlm.nih.gov/pubmed/23785280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003397
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