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PPARγ as a sensor of lipase activity and a target for the lipase inhibitor orlistat
A PPARγ fluorescence polarization (FP) assay was used to measure the release of fatty acid products from triglyceride emulsions during digestion with pancreatic and yeast lipases in a real-time, homogenous assay. Using the same FP assay we show the anti-obesity drug Orlistat is a PPARγ ligand with a...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3681555/ https://ncbi.nlm.nih.gov/pubmed/23566279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-12-48 |
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