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Selective inhibition of vagal afferent nerve pathways regulating cough using Na(v) 1.7 shRNA silencing in guinea pig nodose ganglia
Adeno-associated virus delivery systems and short hairpin RNA (shRNA) were used to selectively silence the voltage-gated sodium channel Na(V) 1.7 in the nodose ganglia of guinea pigs. The cough reflex in these animals was subsequently assessed. Na(V) 1.7 shRNA was delivered to the majority of nodose...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Physiological Society
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3680757/ https://ncbi.nlm.nih.gov/pubmed/23576611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00028.2013 |
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