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Tyrosine-Lipid Peroxide Adducts from Radical Termination: Para-Coupling and Intramolecular Diels-Alder Cyclization

Free radical co-oxidation of polyunsaturated lipids with tyrosine or phenolic analogs of tyrosine gave rise to lipid peroxide-tyrosine (phenol) adducts in both aqueous micellar and organic solutions. The novel adducts were isolated and characterized by 1D and 2D NMR as well as by mass spectrometry....

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Autors principals: Shchepin, Roman, Möller, Matias N., Kim, Hye-young H., Hatch, Duane M., Bartesaghi, Silvina, Kalyanaraman, Balaraman, Radi, Rafael, Porter, Ned A.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677824/
https://ncbi.nlm.nih.gov/pubmed/21090613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja106503a
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