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Off-Target Effect of Endogenous siRNA Derived from RMRP in Human Cells
Endogenous siRNAs (endo-siRNAs) are key regulators of RNA silencing in plants and worms; however, the biogenesis and function of endogenous siRNAs in mammals remain largely unknown. We previously demonstrated that human telomerase reverse transcriptase produces a self-targeting endogenous siRNA from...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Molecular Diversity Preservation International (MDPI)
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3676784/ https://ncbi.nlm.nih.gov/pubmed/23629666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms14059305 |
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