Role of STAT3 in Angiotensin II-Induced Hypertension and Cardiac Remodeling Revealed by Mice Lacking STAT3 Serine 727 Phosphorylation

STAT3 is involved in protection of the heart provided by ischemic preconditioning. However, the role of this transcription factor in the heart in chronic stresses such as hypertension has not been defined. We assessed whether STAT3 is important in hypertension-induced cardiac remodeling using mice w...

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Main Authors: Zouein, Fouad A., Zgheib, Carlos, Hamza, Shereen, Fuseler, John W., Hall, John E., Soljancic, Andrea, Lopez-Ruiz, Arnaldo, Kurdi, Mazen, Booz, George W.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674130/
https://ncbi.nlm.nih.gov/pubmed/23364341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hr.2012.223
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