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Comparative study of guanidine-based and lysine-based brush copolymers for plasmid delivery

Polyethylenimine (PEI), one of the most frequently used polycations for non-viral nucleic acid delivery, exhibits good transfection efficiency to cultured cells but generally has to be used in restricted concentration ranges due to high cytotoxicity. We recently reported a family of HPMA-co-oligolys...

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Autors principals: Carlson, Peter M., Schellinger, Joan G., Pahang, Joshuel A., Johnson, Russell N., Pun, Suzie H.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673726/
https://ncbi.nlm.nih.gov/pubmed/23750319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3BM60079C
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