Nanoscale imaging reveals laterally expanding antimicrobial pores in lipid bilayers

Antimicrobial peptides are postulated to disrupt microbial phospholipid membranes. The prevailing molecular model is based on the formation of stable or transient pores although the direct observation of the fundamental processes is lacking. By combining rational peptide design with topographical (a...

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Main Authors: Rakowska, Paulina D., Jiang, Haibo, Ray, Santanu, Pyne, Alice, Lamarre, Baptiste, Carr, Matthew, Judge, Peter J., Ravi, Jascindra, M. Gerling, Ulla I., Koksch, Beate, Martyna, Glenn J., Hoogenboom, Bart W., Watts, Anthony, Crain, Jason, Grovenor, Chris R. M., Ryadnov, Maxim G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2013
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670350/
https://ncbi.nlm.nih.gov/pubmed/23671080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222824110
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