Nanoscale imaging reveals laterally expanding antimicrobial pores in lipid bilayers

Antimicrobial peptides are postulated to disrupt microbial phospholipid membranes. The prevailing molecular model is based on the formation of stable or transient pores although the direct observation of the fundamental processes is lacking. By combining rational peptide design with topographical (a...

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Main Authors: Rakowska, Paulina D., Jiang, Haibo, Ray, Santanu, Pyne, Alice, Lamarre, Baptiste, Carr, Matthew, Judge, Peter J., Ravi, Jascindra, M. Gerling, Ulla I., Koksch, Beate, Martyna, Glenn J., Hoogenboom, Bart W., Watts, Anthony, Crain, Jason, Grovenor, Chris R. M., Ryadnov, Maxim G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670350/
https://ncbi.nlm.nih.gov/pubmed/23671080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222824110
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