Role of Factor H Binding Protein in Neisseria meningitidis Virulence and Its Potential as a Vaccine Candidate To Broadly Protect against Meningococcal Disease

SUMMARY: Neisseria meningitidis is a Gram-negative microorganism that exists exclusively in humans and can cause devastating invasive disease. Although capsular polysaccharide-based vaccines against serogroups A, C, Y, and W135 are widely available, the pathway to a broadly protective vaccine agains...

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Bibliographische Detailangaben
Hauptverfasser: McNeil, Lisa K., Zagursky, Robert J., Lin, Shuo L., Murphy, Ellen, Zlotnick, Gary W., Hoiseth, Susan K., Jansen, Kathrin U., Anderson, Annaliesa S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668674/
https://ncbi.nlm.nih.gov/pubmed/23699256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.00056-12
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