A triclinic crystal structure of the carboxy-terminal domain of HIV-1 capsid protein with four molecules in the asymmetric unit reveals a novel packing interface

The Gag precursor is the major structural protein of the virion of human immunodeficiency virus-1 (HIV-1). Capsid protein (CA), a cleavage product of Gag, plays an essential role in virus assembly both in Gag-precursor multimerization and in capsid core formation. The carboxy-terminal domain (CTD) o...

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Bibliographic Details
Main Authors: Lampel, Ayala, Yaniv, Oren, Berger, Or, Bacharach, Eran, Gazit, Ehud, Frolow, Felix
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2013
Subjects:
Structural Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668575/
https://ncbi.nlm.nih.gov/pubmed/23722834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113011871
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