TRAIL and proteasome inhibitors combination induces a robust apoptosis in human malignant pleural mesothelioma cells through Mcl-1 and Akt protein cleavages

BACKGROUND: Malignant pleural mesothelioma (MPM) is an aggressive malignancy closely associated with asbestos exposure and extremely resistant to current treatments. It exhibits a steady increase in incidence, thus necessitating an urgent development of effective new treatments. METHODS: Proteasome...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Yuan, Bao-Zhu, Chapman, Joshua, Ding, Min, Wang, Junzhi, Jiang, Binghua, Rojanasakul, Yon, Reynolds, Steven H
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2013
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665596/
https://ncbi.nlm.nih.gov/pubmed/23517112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-140
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы