Cbl-b Is a Critical Regulator of Macrophage Activation Associated With Obesity-Induced Insulin Resistance in Mice

We previously reported the potential involvement of casitas B-cell lymphoma-b (Cbl-b) in aging-related murine insulin resistance. Because obesity also induces macrophage recruitment into adipose tissue, we elucidated here the role of Cbl-b in obesity-related insulin resistance. Cbl-b(+/+) and Cbl-b(...

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Autors principals: Abe, Tomoki, Hirasaka, Katsuya, Kagawa, Sachiko, Kohno, Shohei, Ochi, Arisa, Utsunomiya, Kenro, Sakai, Atsuko, Ohno, Ayako, Teshima-Kondo, Shigetada, Okumura, Yuushi, Oarada, Motoko, Maekawa, Yoichi, Terao, Junji, Mills, Edward M., Nikawa, Takeshi
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2013
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661636/
https://ncbi.nlm.nih.gov/pubmed/23349502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0677
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