A dengue DNA vaccine formulated with Vaxfectin(®) is well tolerated, and elicits strong neutralizing antibody responses to all four dengue serotypes in New Zealand white rabbits

A tetravalent DNA vaccine formulated with Vaxfectin adjuvant was shown to elicit high levels of neutralizing antibody against all four dengue virus serotypes (Porter et al.,(16)), warranting further testing in humans. In preparation for a phase 1 clinical testing, the vaccine and the adjuvant were m...

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Bibliografiske detaljer
Main Authors: Raviprakash, Kanakatte, Luke, Thomas, Doukas, John, Danko, Janine, Porter, Kevin, Burgess, Timothy, Kochel, Tadeusz
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2012
Fag:
Short Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656063/
https://ncbi.nlm.nih.gov/pubmed/23032166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.21806
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