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Exploiting invariant NKT cells to promote T-cell responses to cancer vaccines
Invariant natural killer T (iNKT) cells have the capacity to amplify adaptive immune responses by licensing antigen-presenting cells. A simple vaccine consisting of whole tumor cells pulsed with an iNKT-cell agonist efficiently delivers antigens plus adjuvants to endogenous dendritic cells and has p...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3654595/ https://ncbi.nlm.nih.gov/pubmed/23734325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.23789 |
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