P. aeruginosa Lipopolysaccharide-Induced MUC5AC and CLCA3 Expression Is Partly through Duox1 In Vitro and In Vivo

BACKGROUND: We have previously found that reactive oxygen species (ROS) are involved in Pseudomonas aeruginosa lipopolysaccharide (PA-LPS) induced MUC5AC in airway epithelial cells. Dual oxidase1 (Duox1), a member of NADPH oxidase(Nox), is known to be responsible for ROS production in respiratory tr...

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Main Authors: Li, Wen, Yan, Fugui, Zhou, Hongbin, Lin, Xiaoping, Wu, Yinfang, Chen, Ce, Zhou, Niya, Chen, Zhihua, Li, Jian-dong, Shen, Huahao
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653940/
https://ncbi.nlm.nih.gov/pubmed/23691121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063945
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