Interaction between Obesity and the NFKB1 - 94ins/delATTG Promoter Polymorphism in Relation to Incident Acute Coronary Syndrome: A Follow Up Study in Three Independent Cohorts

INTRODUCTION: The NF-κB transcription factor family regulates several genes encoding pro-inflammatory and anti-inflammatory proteins in adipose tissues and in atherosclerotic plaques. The deletion variant allele of the NFKB1 - 94ins/delATTG promoter polymorphism leads to lower transcript levels of t...

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Autores principales: Stegger, Jakob Gerhard, Schmidt, Erik Berg, Berentzen, Tina Landsvig, Tjønneland, Anne, Vogel, Ulla, Rimm, Eric, Sørensen, Thorkild I. A., Overvad, Kim, Jensen, Majken K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650017/
https://ncbi.nlm.nih.gov/pubmed/23671649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063004
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