The ULb′ Region of the Human Cytomegalovirus Genome Confers an Increased Requirement for the Viral Protein Kinase UL97

We report a requirement for the viral protein kinase UL97 in human cytomegalovirus (HCMV) replication that maps to the ULb′ region of the viral genome. A UL97-null (Δ97) mutant of strain TB40/E, which encodes a full-length ULb′ region, exhibited replication defects, particularly in production of cel...

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Detalhes bibliográficos
Main Authors: Wang, Depeng, Li, Gang, Schauflinger, Martin, Nguyen, Christopher C., Hall, Ellie D., Yurochko, Andrew D., von Einem, Jens, Kamil, Jeremy P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648124/
https://ncbi.nlm.nih.gov/pubmed/23536674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03477-12
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