A CRE/ATF-like site in the upstream regulatory sequence of the human interleukin 1 beta gene is necessary for induction in U937 and THP-1 monocytic cell lines.

Transfection of U937 and THP-1 cells with a recombinant plasmid, pIL1(4.0kb)-CAT, containing 4 kb of the interleukin 1 beta (IL-1 beta) gene upstream regulatory sequence resulted in inducer-dependent expression of chloramphenicol acetyltransferase activity. Treatment of the transfected cells with va...

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Main Authors: Gray, J G, Chandra, G, Clay, W C, Stinnett, S W, Haneline, S A, Lorenz, J J, Patel, I R, Wisely, G B, Furdon, P J, Taylor, J D
格式: Artigo
語言:Inglês
出版: 1993
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC364731/
https://ncbi.nlm.nih.gov/pubmed/8413264
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