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A growth factor-induced kinase phosphorylates the serum response factor at a site that regulates its DNA-binding activity.

A signaling pathway by which growth factors may induce transcription of the c-fos proto-oncogene has been characterized. Growth factor stimulation of quiescent fibroblasts activates a protein kinase cascade that leads to the rapid and transient phosphorylation of the serum response factor (SRF), a r...

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Détails bibliographiques
Auteurs principaux: Rivera, V M, Miranti, C K, Misra, R P, Ginty, D D, Chen, R H, Blenis, J, Greenberg, M E
Format: Artigo
Langue:Inglês
Publié: 1993
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC364685/
https://ncbi.nlm.nih.gov/pubmed/8413226
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