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Pseudomonas aeruginosa disrupts Caenorhabditis elegans iron homeostasis, causing a hypoxic response and death

The opportunistic pathogen Pseudomonas aeruginosa causes serious human infections, but effective treatments and the mechanisms mediating pathogenesis remain elusive. Caenorhabditis elegans shares innate immune pathways with humans, making it invaluable to investigate infection. To determine how P. a...

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Auteurs principaux: Kirienko, Natalia V., Kirienko, Daniel R., Larkins-Ford, Jonah, Wählby, Carolina, Ruvkun, Gary, Ausubel, Frederick M.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641844/
https://ncbi.nlm.nih.gov/pubmed/23601103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2013.03.003
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